visible light

By Targets:	Biochemical Assay Reagents (3) Fluorescent Dye (5) GLUT (1) HCN Channel (2) mGluR (1) Potassium Channel (4) PROTACs (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (1) Metabolic Disease (1) Neurological Disease (5)
Click Chemistry:	Alkynes (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-161092A

KIO-301 chloride (hydrochloride)	HCN Channel Potassium Channel	Others
KIO-301 chloride hydrochloride is an azobenzene photoswitchable compound that blocks voltage-gated ion channels, including hyperpolarization-activated cyclic nucleotide gating (HCN, during exposure to visible light) ) and voltage-gated potassium channels (voltage-gated potassium channels) .

HY-161092

KIO-301 chloride	HCN Channel Potassium Channel	Neurological Disease
KIO-301 chloride is an azobenzene photoswitch compound that can block voltage-gated ion channels, including hyperpolarisation-activated cyclic nucleotide-gated (HCN) and voltage-gated potassium channels during exposure to visible light .

HY-D0367

Fluorescent Brightener 28	Fluorescent Dye	Cancer
Fluorescent Brightener 28 is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations .

HY-161093

PROTAC BRD4 Degrader-23	PROTACs	Cancer
PROTAC BRD4 Degrader-23 (compound 17) is an effective visible-light-controlled degrader. PROTAC BRD4 Degrader-23 can inhibit tumor cell proliferation under 405 nm light irradiation .

HY-136564A

DAD	Potassium Channel	Neurological Disease
DAD is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD is a third-generation photoswitch that responds to visible light. DAD has the potential for restoring visual function .

HY-107689

RuBiNic	Others	Neurological Disease
RuBiNic is a cage compound based on the photochemistry of Ru-bpy complexes and releases nicotine by irradiation with visible light up to 532 nm. RuBiNic is able to induce action potentials in Retzius neurons with 473 nm laser .

HY-13615A

EC-17 disodium salt	Fluorescent Dye	Cancer
EC-17 (disodium salt) is a folate receptor alpha (FRα) targeting contrast agent with fluorescent properties in the visible light spectrum. The peak excitation and emission wavelengths of EC-17 are 470/520 nm.

HY-136564

DAD dichloride	Potassium Channel	Neurological Disease
DAD dichloride is a type of ion channel blocker that blocks voltage-gated potassium channels. DAD dichloride is a third-generation photoswitch that responds to visible light. DAD dichloride has the potential for restoring visual function .

HY-131019

JF-NP-26	mGluR	Neurological Disease
JF-NP-26, an inactive photocaged derivative of raseglurant, is the first caged mGlu5 receptor negative allosteric modulator. Uncaging of JF-NP-26 is elicited with light pulses in the visible spectrum (405 nm). JF-NP-26 induces light-dependent analgesia in models of inflammatory and neuropathic pain in freely behaving animals .

HY-W127709

Chlorophyll b	Biochemical Assay Reagents	Others
Chlorophyll b is decomposed by chlorophyllase to form pheophytin b. This causes its color to change from green to olive brown. It is involved in the harvesting of light energy and its subsequent conversion into chemical energy during photosynthesis. Along with chlorophyll a, it plays a key role in the ability of plants to adapt to varying light intensities. The visible spectrum that is not absorbed when only chlorophyll a is present in the LHC.

HY-162132

WZB117-PPG	GLUT	Cancer
WZB117-PPG is a glucose transporter 1 (GLUT1) inhibitor with anticancer activity. WZB117-PPG has remarkable photolysis efficiency and cytotoxicity to cancer cells under visible light irradiation .

HY-162045

Ru-4T	Others	Cancer
Ru-4T is a phototherapy agent. Ru-4T has phototherapeutic efficacy (PI = 114,000) against melanoma cells (SK-MEL-28) under broad-band visible light (400-700 nm) with EC₅₀ values of 740 pM .

HY-144368

CO delivery molecule 1	Others	Inflammation/Immunology
CO delivery molecule 1 (compound 4) localizes to the endoplasmic reticulum, mitochondria, and lysosomes. Subcellular localization of CO delivery molecule 1 results in CO-induced toxicity effects. Anti-inflammatory effects of CO delivery molecule 1, as measured by TNF-α suppression, occur at the nanomolar level in the absence of CO release, and are enhanced with visible-light-induced CO release .

HY-126821

Fluo-3	Fluorescent Dye	Others
Fluo-3 and related molecule Fluo3/AM are used as a fluorescence indicator of intracellular calcium (Ca ²⁺). Fluo-3 may be use for flow cytometry and confocal laser scanning microscopy using visible light excitation (compatible with argon laser sources operating at 488 nm). Fluorescence intensity increases about 40-fold after calcium binding.

HY-W075707

FeTCPP Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride	Biochemical Assay Reagents	Others
FeTCPP (Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride) is a metallic porphyrin compound formed by the coordination of a central iron ion (Fe ³⁺) with four 4-carboxyphenylporphyrins (TCPP). FeTCPP can be used as a catalyst for catalytic, electrochemical, photochemical and biomedical research. FeTCPP has high photocatalytic performance for p-nitrophenol under visible light. FeTCPP also has peroxisase-like activity, which is used in bionic catalysis research .

HY-D0989

Rhod-2 AM 5+ Cited Publications	Fluorescent Dye	Others
Rhod-2 is a high-affinity visible light excitation wavelength Ca ²⁺ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .

HY-158231

Polyether F127 Diacrylate F127DA	Biochemical Assay Reagents	Others
Polyether F127 Diacrylate (F127DA) is an acrylated triblock copolymer of polyethylene glycol-polypropylene glycol-polyethylene glycol. Polyether F127 Diacrylate rapidly cross-links and solidifies into a gel under the action of UV and visible light with photoinitiators. Polyether F127 Diacrylate has excellent thermogelling (heating gel) properties and good biosafety, and can be used in biomedical fields, such as drug carriers, wound dressings, cell carrier shear protectants, 3D printing, etc .

HY-139337

SMCy5.5	Fluorescent Dye	Metabolic Disease
SMCy5.5 is an SMCy dye used for lipid droplet labeling with a very high two-photon absorption cross-section. SMCy, unlike the well-known lipid droplet marker Nile Red, has narrow absorption and emission bands in visible light, allowing for multicolor imaging. SMCy is shown to be compatible with fixation, producing high-quality 3D images of lipid droplets in cells and tissues. The high brightness of SMCy5.5 enables efficient tracking and imaging of lipid droplet exchange between adipocytes .

Cat. No.	Product Name	Type

HY-D0989

Rhod-2 AM 5+ Cited Publications	Fluorescent Dyes/Probes
Rhod-2 is a high-affinity visible light excitation wavelength Ca ²⁺ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .

Rhod-2 AM

5+ Cited Publications

Fluorescent Dyes/Probes

Rhod-2 is a high-affinity visible light excitation wavelength Ca ²⁺ fluorescent probe, Rhod-2, AM is an acetyl methyl ester derivative of Rhod-2, which has cell membrane permeability and can easily enter cells with simple culture. Once it enters the cell, it is sheared by its lactesterase to produce Rhod-2 without membrane permeability, which remains in the cell to perform the corresponding physiological functions. Maximum excitation/emission wavelength: 549/578 nm .

HY-D0367

Fluorescent Brightener 28	Fluorescent Dyes/Probes
Fluorescent Brightener 28 is a visible light emitting diode (LED)-light sensitive photoinitiator for free radical photopolymerizations .

HY-126821

Fluo-3	Fluorescent Dyes/Probes
Fluo-3 and related molecule Fluo3/AM are used as a fluorescence indicator of intracellular calcium (Ca ²⁺). Fluo-3 may be use for flow cytometry and confocal laser scanning microscopy using visible light excitation (compatible with argon laser sources operating at 488 nm). Fluorescence intensity increases about 40-fold after calcium binding.

HY-139337

SMCy5.5	Fluorescent Dyes/Probes
SMCy5.5 is an SMCy dye used for lipid droplet labeling with a very high two-photon absorption cross-section. SMCy, unlike the well-known lipid droplet marker Nile Red, has narrow absorption and emission bands in visible light, allowing for multicolor imaging. SMCy is shown to be compatible with fixation, producing high-quality 3D images of lipid droplets in cells and tissues. The high brightness of SMCy5.5 enables efficient tracking and imaging of lipid droplet exchange between adipocytes .

SMCy5.5

Fluorescent Dyes/Probes

SMCy5.5 is an SMCy dye used for lipid droplet labeling with a very high two-photon absorption cross-section. SMCy, unlike the well-known lipid droplet marker Nile Red, has narrow absorption and emission bands in visible light, allowing for multicolor imaging. SMCy is shown to be compatible with fixation, producing high-quality 3D images of lipid droplets in cells and tissues. The high brightness of SMCy5.5 enables efficient tracking and imaging of lipid droplet exchange between adipocytes .

Cat. No.	Product Name	Type

HY-W127709

Chlorophyll b	Biochemical Assay Reagents
Chlorophyll b is decomposed by chlorophyllase to form pheophytin b. This causes its color to change from green to olive brown. It is involved in the harvesting of light energy and its subsequent conversion into chemical energy during photosynthesis. Along with chlorophyll a, it plays a key role in the ability of plants to adapt to varying light intensities. The visible spectrum that is not absorbed when only chlorophyll a is present in the LHC.

Chlorophyll b

Biochemical Assay Reagents

Chlorophyll b is decomposed by chlorophyllase to form pheophytin b. This causes its color to change from green to olive brown. It is involved in the harvesting of light energy and its subsequent conversion into chemical energy during photosynthesis. Along with chlorophyll a, it plays a key role in the ability of plants to adapt to varying light intensities. The visible spectrum that is not absorbed when only chlorophyll a is present in the LHC.

HY-W075707

FeTCPP Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride	Biochemical Assay Reagents
FeTCPP (Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride) is a metallic porphyrin compound formed by the coordination of a central iron ion (Fe ³⁺) with four 4-carboxyphenylporphyrins (TCPP). FeTCPP can be used as a catalyst for catalytic, electrochemical, photochemical and biomedical research. FeTCPP has high photocatalytic performance for p-nitrophenol under visible light. FeTCPP also has peroxisase-like activity, which is used in bionic catalysis research .

FeTCPP

Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride

Biochemical Assay Reagents

FeTCPP (Iron(III) meso-Tetra(4-carboxyphenyl)porphine chloride) is a metallic porphyrin compound formed by the coordination of a central iron ion (Fe ³⁺) with four 4-carboxyphenylporphyrins (TCPP). FeTCPP can be used as a catalyst for catalytic, electrochemical, photochemical and biomedical research. FeTCPP has high photocatalytic performance for p-nitrophenol under visible light. FeTCPP also has peroxisase-like activity, which is used in bionic catalysis research .

HY-158231

Polyether F127 Diacrylate F127DA	3D Bioprintig
Polyether F127 Diacrylate (F127DA) is an acrylated triblock copolymer of polyethylene glycol-polypropylene glycol-polyethylene glycol. Polyether F127 Diacrylate rapidly cross-links and solidifies into a gel under the action of UV and visible light with photoinitiators. Polyether F127 Diacrylate has excellent thermogelling (heating gel) properties and good biosafety, and can be used in biomedical fields, such as drug carriers, wound dressings, cell carrier shear protectants, 3D printing, etc .

Polyether F127 Diacrylate

F127DA

3D Bioprintig

Polyether F127 Diacrylate (F127DA) is an acrylated triblock copolymer of polyethylene glycol-polypropylene glycol-polyethylene glycol. Polyether F127 Diacrylate rapidly cross-links and solidifies into a gel under the action of UV and visible light with photoinitiators. Polyether F127 Diacrylate has excellent thermogelling (heating gel) properties and good biosafety, and can be used in biomedical fields, such as drug carriers, wound dressings, cell carrier shear protectants, 3D printing, etc .

Cat. No.	Product Name		Classification

HY-139337

SMCy5.5		Alkynes
SMCy5.5 is an SMCy dye used for lipid droplet labeling with a very high two-photon absorption cross-section. SMCy, unlike the well-known lipid droplet marker Nile Red, has narrow absorption and emission bands in visible light, allowing for multicolor imaging. SMCy is shown to be compatible with fixation, producing high-quality 3D images of lipid droplets in cells and tissues. The high brightness of SMCy5.5 enables efficient tracking and imaging of lipid droplet exchange between adipocytes .

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Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Click Chemistry